产品货号：
Z34173
中文名称：
SMURF2抗体
英文名称：
Anti-SMURF2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMURF2 Antibody |
| 指标别名 | SMAD specific E3 ubiquitin protein ligase 2;SMURF2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | SMURF2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human SMURF 2 E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. |
| 实际分子量 | 86KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene.The SMURF2 gene is mapped to chromosome 17q22-q23 based on sequence similarity between the SMURF2 sequence and a genomic contig.SMURF2 is a HECT domain E3 ubiquitin ligase involved in degradation of SMADs,TGF-beta receptor (TGFBR),and other substrates.It also functions in regulation of neuronal and planar cell polarity,induction of senescence,and tumor suppression. |
| Uniprot ID | Q9HAU4 |
| 推荐稀释比 | Western blot (WB) 1:400～800 |
相关搜索：SMURF2抗体，SMURF2单抗，Anti-SMURF2 Antibody